所属 医学部 医学科（東京女子医科大学病院） 職種 准教授
|表題||Skeletal muscle index determined by bioelectrical impedance analysis is a determinant of exercise capacity and a prognostic predictor in patients with congenital heart disease.|
|掲載誌名||正式名：Journal of cardiology|
略 称：J Cardiol
|出版社||Elsevier publishes on behalf of the Japanese College of Cardiology|
|著者・共著者||SATO Masaki†, INAI Kei*, ASAGAI Seiji, HARADA Gen, SHIMADA Eriko, SUGIYAMA Hisashi|
|概要||RESULTS:The multivariate analysis revealed a significant correlation between peakVO2 and EI (r = -0.55) and peakVO2 and SMI (r = 0.49). The receiver operating characteristic curve analysis showed that the EI cut-off for peakVO2 <20 ml/kg/min was 0.386 [area under the curve (AUC), 0.77; sensitivity, 0.67; specificity 0.76], and the SMI cut-off was 7.6 kg/m2 (AUC, 0.78; sensitivity, 0.76; specificity 0.75). Compared with patients who had biventricular morphology, patients with single ventricular morphology had a higher EI (mean, 0.381 vs. 0.387, respectively) and lower SMI (8.5 vs. 7.7, respectively), resulting in a lower peakVO2 (27.1 vs. 20.8, respectively). The Kaplan-Meier analysis showed that a low SMI was associated with an increased risk of future heart failure-related admissions.
CONCLUSIONS:SMI determined by BIA is a determinant of exercise capacity and can be used as a prognostic predictor in patients with CHD.