SUTO Chikako
   Department   School of Medicine(Tokyo Women's Medical University Adachi Medical Center), School of Medicine
   Position   Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Effect of perioperative glycemic control in progression of diabetic retinopathy and maculopathy.
Journal Formal name：Archives of ophthalmology (Chicago, Ill. : 1960)
Abbreviation：Arch Ophthalmol
ISSN code：00039950/00039950
Domestic / ForeginForegin
Volume, Issue, Page 124(1),pp.38-45
Author and coauthor Suto Chikako†, Hori Sadao, Kato Satoshi, Muraoka Kanemitsu, Kitano Shigehiko
Authorship Lead author,Corresponding author
Publication date 2006/01
Summary OBJECTIVE:To evaluate the contribution of perioperative glycemic control to progression of diabetic retinopathy and maculopathy.METHODS:Postoperative progression of diabetic retinopathy and maculopathy were compared in 87 patients with type 2 diabetes mellitus who underwent monocular phacoemulsification cataract surgery performed by a single surgeon. Twenty-seven patients had had poor glycemic control preoperatively and underwent rapid preoperative glycemic correction; 30 patients had poor control preoperatively that was not corrected postoperatively; and 30 patients had good preoperative glycemic control. The grade of diabetic retinopathy and maculopathy in the operated-on eye and the fellow eye was assessed preoperatively and for 12 months postoperatively.RESULTS:There were no significant differences in the progression rate of diabetic retinopathy among the 3 groups (P = .27). However, the progression rate of diabetic maculopathy was significantly higher in the group that underwent rapid control than in the other 2 groups (P = .02). Patients with moderate to severe nonproliferative diabetic retinopathy preoperatively in the rapid control group had significantly higher progression rates of diabetic retinopathy and maculopathy (P = .002 and .008, respectively).CONCLUSIONS:Rapid preoperative glycemic control should be avoided in patients with moderate to severe nonproliferative diabetic retinopathy because it may increase the risk of postoperative progression of retinopathy and maculopathy.
DOI 10.1001/archopht.124.1.38
PMID 16401783