長尾 充展
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Associate Professor
Article types Review article
Language English
Peer review Peer reviewed
Title Measurement of heterogeneous distribution on Technegas SPECT images by three-dimensional fractal analysis.
Journal Formal name:Annals of nuclear medicine
Abbreviation:Ann Nucl Med
ISSN code:(0914-7187)0914-7187(Linking)
Domestic / ForeginDomestic
Volume, Issue, Page 16(6),pp.369-76
Author and coauthor Nagao Michinobu, Murase Kenya
Authorship Lead author,Corresponding author
Publication date 2002/09
Summary This review article describes a method for quantifying heterogeneous distribution on Technegas (99mTc-carbon particle radioaerosol) SPECT images by three-dimensional fractal analysis (3D-FA). Technegas SPECT was performed to quantify the severity of pulmonary emphysema. We delineated the SPECT images by using five cut-offs (15, 20, 25, 30 and 35% of the maximal voxel radioactivity), and measured the total number of voxels in the areas surrounded by the contours obtained with each cut-off level. We calculated fractal dimensions from the relationship between the total number of voxels and the cut-off levels transformed into natural logarithms. The fractal dimension derived from 3D-FA is the relative and objective measurement, which can assess the heterogeneous distribution on Technegas SPECT images. The fractal dimension strongly correlate pulmonary function in patients with emphysema and well documented the overall and regional severity of emphysema.
DOI 10.1007/BF02990073
PMID 12416574