長尾　充展
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Associate Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Detection of ground-glass opacities by use of hybrid iterative reconstruction (iDose) and low-dose 256-section computed tomography: a phantom study.
Journal Formal name：Radiological physics and technology
Abbreviation：Radiol Phys Technol
ISSN code：(1865-0341)1865-0333(Linking)
Domestic / ForeginForegin
Volume, Issue, Page 6(2),pp.299-304
Author and coauthor Higuchi Ko, Nagao Michinobu, Matsuo Yoshio, Sunami Shunya, Kamitani Takeshi, Jinnouchi Mikako, Yonezawa Masato, Yamasaki Yuzo, Yabuuchi Hidetake, Hatkenaka Masamitsu, Honda Hiroshi
Authorship 2nd author
Publication date 2013/07
Summary The detection of ground-glass opacities (GGOs) is an important issue in lung cancer screening with low-dose CT. The iterative reconstruction (IR) technique has the ability to improve the image quality relative to the filtered back projection (FBP) technique with low-dose CT. Our purpose was to investigate the ability to detect GGO in a chest phantom using a low-dose CT and hybrid IR, named iDose. Simulated GGOs in a chest phantom were scanned with 256-section CT at tube current second products of 20, 50, 100, and 200 mAs. Five radiologists visually assessed the detectability of GGOs in the phantom. The contrast-to-noise ratio (CNR) for GGOs was used as an estimate of image quality. Comparison of the detectability and CNR between standard images with 200 mAs-FBP and low-dose images with 20, 50, and 100-mAs FBP/iDose were performed by ANOVA with Dunnett's and Tukey's test. The detectability was significantly lower at 20-mAs FBP/iDose and 50-mAs FBP than that at 200-mAs FBP (p < 0.05). There was no significant difference between 50-mAs iDose and 200-mAs FBP and between 100-mAs iDose/FBP and 200-mAs FBP. The CNR was significantly higher on iDose images than that on FBP images at each mAs value. The CNR at 200-mAs FBP was the same as that at 50-mAs iDose (CNR:1.8). The hybrid IR technique and low-dose CT imaging with 50 mAs enabled noise and to maintain the detectability for GGOs in a chest phantom that is equivalent to the reference acquisitions of 200 mAs with FBP.
DOI 10.1007/s12194-013-0200-y
PMID 23400447