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Michio Otsuki
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor and Division head |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | Debulking surgery for functional pleural dissemination of parathyroid carcinoma-case report |
| Journal | Formal name：Journal of cardiothoracic surgery Abbreviation：J Cardiothorac Surg ISSN code：17498090/17498090 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 16(1),pp.86 |
| Author and coauthor | Kawagishi Sachi, Funaki Soichiro, Ose Naoko, Kimura Kenji, Mukai Kosuke, Otsuki Michio, Shintani Yasushi |
| Publication date | 2021/04 |
| Summary | BACKGROUND:A rare cause of primary hyperparathyroidism (PHPT) is a parathyroid carcinoma. Hypercalcemia with an elevated parathyroid hormone (PTH) level seen in recurrent and metastasis disease cases is often refractory to medical therapy, thus surgical resection is recommended when possible. We performed debulking surgery for pleural dissemination of parathyroid cancer for improvement of symptoms in a patient with hypercalcemia.CASE PRESENTATION:A 30-year-old male with hypercalcemia was diagnosed with parathyroid cancer. Following surgery, intact PTH level elevation and hypercalcemia progression due to recurrent disease were noted. An active status of functional left pleural dissemination was revealed in 99mTc-methoxyisobutylisonitrile and somatostatin receptor scintigraphy results, but not in the area of pulmonary metastasis, and debulking surgery was performed. Thereafter, the PTH level was decreased temporarily and activities of daily living improved.CONCLUSION:Aggressive resection of metastatic disease in patients with a parathyroid carcinoma is taken into consideration to control hypercalcemia. |
| DOI | 10.1186/s13019-021-01477-z |
| PMID | 33858470 |