Michio Otsuki
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Case report
Language English
Peer review Peer reviewed
Title Oral Contraceptive Disturbedthe Recovery of the Adrenal Function after Adrenalectomy in Cushing Syndrome: A Case Report
Journal Formal name:Internal Medicine
Abbreviation:Intern Med
ISSN code:09182918
Domestic / ForeginDomestic
Volume, Issue, Page 60,pp.901-903
Author and coauthor Okuno, Y. Kawata, S. Shimizu, Y. Mukai, K. Otsuki, M. Shimomura, I.
Authorship Corresponding author
Publication date 2020
Summary Estrogen is known to increase exogenous corticosteroid levels. In this case, a 27-year-old Japanese woman was referred to our hospital for examination of an adrenal tumor and was diagnosed with Cushing syndrome. Resection of the tumor resulted in secondary adrenal insufficiency. She also developed microcytic anemia due to hypermenorrhea, which was masked by Cushing syndrome. An oral contraceptive was administered for the treatment of hypermenorrhea, but this led to a marked increase in serum cortisol and the reduction of plasma ACTH, disturbing the recovery of the adrenal function. Attention is required when oral contraceptives are used to treat hypermenorrhea masked by Cushing syndrome.
DOI 10.2169/internalmedicine.5462-20
Document No. 33055479