Michio Otsuki    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Professor and Division head
Article types	Case report
Language	English
Peer review	Peer reviewed
Title	A Case of Hypocalcemia with Severe Vitamin D Deficiency following Treatment for Graves'Disease with Methimazole
Journal	Formal name：Case reports in endocrinology Abbreviation：Case Rep Endocrinol ISSN code：20906501 (Print)2090651X (Linking)
Domestic / Foregin	Foregin
Volume, Issue, Page	2013,pp.512671
Author and coauthor	Miyashita, K. Yasuda, T. Kaneto, H. Kuroda, A. Kitamura, T. Otsuki, M. Okamoto, Y. Hamada, N. Matsuhisa, M. Shimomura, I.
Publication date	2013
Summary	We herein report the case of a 41-year-old Japanese female office worker who developed symptomatic hypocalcemia with severe vitamin D deficiency following treatment for Graves'disease with methimazole. The patient's hypocalcemia was mainly caused by vitamin D deficiency due to unbalanced diets and inadequate exposure to sunlight in addition to the resolution of hyperthyroidism. Vitamin D deficiency is increasing worldwide, and it has been more recently shown to relate to the pathogenesis of Graves'disease. However, vitamin D deficiency as a cause of hypocalcemia has received little attention. Taken together, this case suggests that we should take more care in calcium kinetics and vitamin D status during treatment for Graves'disease with antithyroid drugs.
DOI	10.1155/2013/512671
Document No.	23710380