モリモト　サトシ   MORIMOTO Satoshi   森本　聡    所属   医学部 医学科（東京女子医科大学病院）    職種   准教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Trichosporon cutaneum fungemia in patients with acute myeloblastic leukemia and measurement of serum D-arabinitol, Candida antigen (CAND-TEC), and beta-D-glucan.
掲載誌名	正式名：Annals of hematology 略　 称：Ann Hematol ISSNコード：09395555/09395555
掲載区分	国外
巻・号・頁	68(3),pp.159-61
著者・共著者	Morimoto S†*, Shimazaki C, Goto H, Hirata Y, Tasumi T, Yamagata N, Hirata T, Ashihara E, Inaba T, Fujita N
担当区分	筆頭著者,責任著者
発行年月	1994/03
概要	Two patients with acute myeloblastic leukemia are described who developed fungemia due to Trichosporon cutaneum. Fungemia occurred at the leukocyte nadir following the administration of anti-cancer chemotherapy. One patient was cured but the other died. Both patients received prednisolone continuously and had central venous catheters in place for parenteral hyperalimentation. T. cutaneum isolates were resistant to 5-fluorocytosine and moderately susceptible to fluconazole. One case was complicated by endophthalmitis due to T. cutaneum; this is the second report of such a complication in the world. We investigated the serum levels of beta-D-glucan, D-arabinitol, and Candida antigen (CAND-TEC); beta-D-glucan was elevated in both cases, which suggests that simultaneous measurements of these laboratory values are useful for the diagnosis and possibly for the evaluation of therapy for this fungal infection.
DOI	10.1007/BF01727422
PMID	8167183