MORIMOTO Satoshi
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Associate Professor
Article types Case report
Language English
Peer review Peer reviewed
Title Community-acquired Clostridium difficile-associated diarrhea in a patient on chronic peritoneal dialysis.
Journal Formal name:Clinical nephrology
Abbreviation:Clin Nephrol
ISSN code:03010430/03010430
Domestic / ForeginForegin
Volume, Issue, Page 74(2),pp.141-3
Author and coauthor Seo M, Takahashi N, Morita T, Morimoto S, Iwasaka T
Publication date 2010/08
Summary A 66-year-old woman on chronic peritoneal dialysis was admitted because of intermittent diarrhea and abdominal pain, and anorexia for 1 month. She had not been given antibiotics nor hospitalized for at least 6 months prior to the onset of symptoms. Clostridium difficile and its toxin were detected in the stool and Clostridium difficile-associated diarrhea (CDAD) was diagnosed. Colonoscopic examination revealed pseudomembrane formation and colitis in the whole colon. Clostridium difficile and its toxin became negative 12 days after vancomycin administration. Thus, clinical suspicion to CDAD is important in dialysis patients presenting with abdominal symptoms even if it is apparently community-acquired with no history of antibiotic use and hospitalization.
DOI 10.5414/cnp74141
PMID 20630134