MORIMOTO Satoshi    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Associate Professor
Article types	Original article
Language	English
Peer review	Peer reviewed
Title	Characteristics of 20-year survivors undergoing maintenance hemodialysis.
Journal	Formal name：Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Abbreviation：Ther Apher Dial ISSN code：17449987/17449979
Domestic / Foregin	Foregin
Volume, Issue, Page	14(6),pp.547-51
Author and coauthor	Morimoto Satoshi†*, Nishioka Hiroaki, Morita Tatsuyori, Jo Fusakazu, Someya Kazunori, Nakahigashi Mitsutaka, Kusabe Makiko, Ueda Hiroko, Takahashi Nobuyuki, Iwasaka Toshiji, Maki Kei
Authorship	Lead author
Publication date	2010/12
Summary	Hemodialysis techniques have improved remarkably in recent decades and the number of long-term survivors among patients with end-stage renal disease has increased. The mortality rate of hemodialysis patients has been reported to be low in Japan. However, the long-term survival rate of dialysis patients is still low: 23.6% for 15 years and 17.4% for 20 years, even in Japan, and background information on patients undergoing hemodialysis therapy for more than 20 years is scarce in this country. In the present study, we investigated the characteristics of 20-year survivors undergoing maintenance hemodialysis at our medical center. We compared the characteristics of hemodialysis patients who had survived for more than 20 years after the initiation of hemodialysis with those of patients who started hemodialysis at the same time and had already died. No patient among those who were still alive had diabetes mellitus while 15% of patients who had died had diabetes mellitus at the time of initiation of hemodialysis. Age, cardiothoracic ratio, and serum levels of total cholesterol and triglyceride 6 months after the initiation of hemodialysis, as well as decreases in body weight per year were significantly lower in those who had survived than in those who had died. These results suggest that long-term hemodialysis survivors are characterized by (i) initiation of hemodialysis at a young age (ii) being free of diabetes mellitus (iii) a well-controlled cardiothoracic ratio (iv) small successive change in body weight, and (v) being free of hypercholesterolemia and hypertriglyceridemia.
DOI	10.1111/j.1744-9987.2010.00846.x
PMID	21118361