モリモト　サトシ   MORIMOTO Satoshi   森本　聡    所属   医学部 医学科（東京女子医科大学病院）    職種   准教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Loperamide therapy in a patient with diarrhea and resistant hypertension.
掲載誌名	正式名：American journal of hypertension 略　 称：Am J Hypertens ISSNコード：08957061/08957061
掲載区分	国外
巻・号・頁	13(4 Pt 1),pp.431-2
著者・共著者	Morimoto S†*, Sasaki S, Itoh H, Nakata T, Takeda K, Nakagawa M
担当区分	2nd著者
発行年月	2000/04
概要	A 65-year-old man was admitted to our hospital for resistant essential hypertension. He had a past history of bowel resections due to Crohn's disease. We assumed that in this patient insufficient drug absorption might be a cause of resistant hypertension and that even increased antihypertensive regimens would fail to decrease blood pressure. We administered loperamide, which may increase drug absorption from the residual intestine. Blood pressure was successfully decreased, with a concomitant increase in blood concentration of antihypertensive drugs. In patients with impaired drug absorption, we should make an effort to restore drug obstruction before considering increased drug regimens.
DOI	10.1016/s0895-7061(99)00231-9
PMID	10821347