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ARIIZUMI Shunichi
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Associate Professor |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | Atypical Sarcoidosis Diagnosed by Massive Splenomegaly. |
| Journal | Formal name：Internal medicine Abbreviation：Intern Med ISSN code：13497235/09182918 |
| Domestic / Foregin | Domestic |
| Volume, Issue, Page | 59(5),pp.641-648 |
| Author and coauthor | SAITO Satomi†, KODAMA Kazuhisa, KOGISO Tomomi*, YAMANASHI Yuki, TANIAI Makiko, ARIIZUMI Shunichi, YAMAMOTO Masakazu, TOKUSHIGE Katsutoshi |
| Publication date | 2020/03 |
| Summary | We examined a 22-year-old woman who was admitted to our hospital with abdominal distention. At 19 years of age, the patient presented with hepatosplenomegaly. She was examined several times in another hospital; however, the cause was unidentified. Our evaluation showed severe pancytopenia and a spleen 13×24 cm in size. The serum levels of angiotensin-converting enzyme and lysozyme were elevated. She was diagnosed with liver sarcoidosis based on non-caseating epithelioid granuloma in liver biopsy tissue. To improve the symptoms, splenectomy was performed, and her pancytopenia and symptoms improved. Sarcoidosis should be considered in cases of massive splenomegaly. |
| DOI | 10.2169/internalmedicine.3646-19 |
| PMID | 31666466 |