ARIIZUMI Shunichi    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Associate Professor
Article types	Original article
Language	English
Peer review	Non peer reviewed
Title	Intrahepatic cholangiocarcinoma.
Journal	Formal name：Seminars in diagnostic pathology Abbreviation：Semin Diagn Pathol ISSN code：(0740-2570)0740-2570(Linking)
Domestic / Foregin	Foregin
Volume, Issue, Page	34(2),pp.160-166
Author and coauthor	NAKANO Masayuki†*, ARIIZUMI Shunichi, YAMAMOTO Msakazu
Authorship	2nd author
Publication date	2017/03
Summary	Cholangiocarcinoma, also referred to as cholangiocellular carcinoma (particularly in Japan), develops along the biliary tract. The tumor may be intra- or extrahepatic and have different features with specific treatments based on the site of origin. Guidelines for diagnosis and management of cholangiorcarcinoma, such as those proposed by EASL (European Association for the Study of the Liver)1 and the Mayo Clinic2 classify the tumor into intrahepatic, perihilar, and distal cholangiocarcinoma. There are three main macroscopic patterns of growth of cholangiocarcinoma: mass-forming, periductal-infiltrating and intraductal. A combination of mass-forming and periductal infiltrating tumors have been shown to have a poor prognosis.3 Intrahepatic cholangiocarcinoma (ICC) comprises two microscopic subtypes: bile duct and cholangiolar.4 The bile duct subtype has tall columnar cells that form large glands, whereas cholangiolar tumors are composed of cuboidal and low columnar cells. Patients with cholangiolar tumors, referred to as cholangiolocellular carcinoma, reportedly have a better 5-year survival rate than those with the bile duct type.4.
DOI	10.1053/j.semdp.2016.12.012
PMID	28094162