KURODA Hajime
   Department   School of Medicine(Tokyo Women's Medical University Adachi Medical Center), School of Medicine
   Position   Professor
Article types Case report
Language English
Peer review Peer reviewed
Title Laparoscopy-assisted total gastrectomy for advanced gastric cancer with carcinomatous ascites after S1 plus cisplatin chemotherapy: a case report.
Journal Formal name:Surgical laparoscopy, endoscopy & percutaneous techniques
Abbreviation:Surg Laparosc Endosc Percutan Tech
ISSN code:15344908/15304515
Domestic / ForeginForegin
Volume, Issue, Page 20(6),pp.e206-10
Author and coauthor Ohdaira Hironori, Suzuki Yutaka, Tsutsui Mai, Iwasaki Taizo, Arita Munefumi, Noro Takuji, Kawasaki Naruo, Ohara Tadashi, Yoshino Keiichi, Kuroda Hajime, Kitajima Masaki
Publication date 2010/12
Summary A 29-year-old man with a type 4 tumor, in the lower third of the stomach, and carcinomatous ascites was diagnosed by aspiration cytology of the ascitic fluid. Curative resection was considered impossible, and S1 (120 mg/d) and cisplatin (90 mg/d) were given for 21 days in 1 course. The cancer lesion showed marked remission (partial response), and the ascites completely disappeared after the fourth course. Twenty-five days after completion of the S1 treatment, laparoscopy-assisted total gastrectomy was performed. Histopathological examination showed no remnant cancer cells in the resected specimen and no lymph node metastases. The tumor was replaced with fibrosis having a granulomatous change. The patient's postoperative course was uneventful. The patient was continued with S1 monotherapy after surgery, and no signs of recurrence or metastases have been seen on any examination 12 months after the surgery.
DOI 10.1097/SLE.0b013e3181fd83cd
PMID 21150404