クロダ　ハジメ   KURODA Hajime   黒田　一    所属   医学部 医学科（附属足立医療センター）    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Clinicopathological study of breast tissue in female-to-male transsexuals.
掲載誌名	正式名：Surgery today 略　 称：Surg Today ISSNコード：09411291/09411291
掲載区分	国外
巻・号・頁	38(12),pp.1067-71
著者・共著者	Kuroda Hajime†*, Ohnisi Kiyoshi, Sakamoto Goi, Itoyama Shinji
担当区分	筆頭著者,責任著者
発行年月	2008
概要	PURPOSE:Gender identity disorder is defined as persistent feelings of gender discomfort and the inappropriateness of one's anatomical sex. To study the effects of androgens on female breast tissue, we examined mammary glands from female-to-male transsexual (FTMT) women using androgen therapy and from those not using androgen therapy.METHODS:Female-to-male transsexual breast tissue is a rare specimen in surgical pathology and there are no well-defined guidelines for its examination. We evaluated the clinicopathologic findings of 186 FTMT mammary glands.RESULTS:The patients' ages at presentation ranged from 18 to 49 years (mean 27.4 years). We detected breast carcinoma in only 1 of 130 FTMT women who had not used androgen therapy and in none of 56 FTMT women who had used androgen therapy.CONCLUSION:We described the histopathological morphology of FTMT breast tissue. The frequency of carcinoma and hyperplasia did not differ significantly between FTMT women who had used androgen therapy and those who had not. These findings suggest that androgen does not alter the risk of carcinoma developing in the mammary glands of FTMT women.
DOI	10.1007/s00595-007-3758-3
PMID	19039630