クロダ　ハジメ   KURODA Hajime   黒田　一    所属   医学部 医学科（附属足立医療センター）    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Clinical and pathologic features of fibroadenoma of the mastopathic type.
掲載誌名	正式名：Surgery today 略　 称：Surg Today ISSNコード：09411291/09411291
掲載区分	国外
巻・号・頁	36(7),pp.590-5
著者・共著者	Kuroda Hajime†*, Takeuchi Ikuya, Ohnishi Kiyoshi, Sakamoto Goi, Akiyama Futoshi, Toyozumi Yasuo, Momose Shuji, Tamaru Jun-Ichi, Itoyama Shinji
担当区分	筆頭著者,責任著者
発行年月	2006
概要	PURPOSE:Fibroadenoma with mastopathic change (FAM) is a relatively uncommon subtype of fibroadenoma of the breast, with a high incidence of pathological misdiagnosis. This histological subtype remains poorly understood because of its rarity. Many questions remain unanswered about its clinicopathological importance, especially in the differential diagnosis of breast cancers.METHODS:Among 218 breast fibroadenomas surgically resected as excisional biopsies at our institute between 1990 and 2004, 19 were pathologically diagnosed as FAM. We reviewed these 19 patients.RESULTS:The ages of the patients ranged from 20 to 51 years (mean 36.8 years). The tumor sizes ranged from 0.8 to 7 cm (mean 2.1 cm). Six of the 19 patients underwent core needle biopsy, resulting in a diagnosis of fibroadenoma in four patients and atypical ductal hyperplasia in two patients. Ultrasonography showed findings suggestive of solid tubular carcinoma in seven patients, fibroadenoma in ten patients, and unspecific malignant tumors in two. They were not specified clinically.CONCLUSION:Recognition of this distinctive variant of fibroadenoma is important because it resembles intraductal carcinoma and is increasing in incidence. It is crucial to distinguish FAM from intraductal carcinoma in biopsy specimens. Thus, not only pathologists but also clinicians must be able to recognize this type of fibroadenoma, and cooperate closely to establish an accurate diagnosis.
DOI	10.1007/s00595-006-3206-9
PMID	16794792