OKANO Teruo
   Department   Research Institutes and Facilities, Research Institutes and Facilities
   Position  
Article types Original article
Language English
Peer review Peer reviewed
Title Analysis of soluble vascular endothelial growth factor receptor-1 secreted from cultured corneal and oral mucosal epithelial cell sheets in vitro.
Journal Formal name:The British journal of ophthalmology
Abbreviation:Br J Ophthalmol
ISSN code:(1468-2079)0007-1161(Linking)
Domestic / ForeginForegin
Volume, Issue, Page 93(2),pp.263-7
Author and coauthor Kanayama S†, Nishida K, Yamato M, Hayashi R, Maeda N, Okano T, Tano Y
Publication date 2009/02
Summary CCE secreted a significantly higher amount of soluble VEGFr-1 than did COE. Recombinant soluble VEGFr-1 significantly suppressed HUVEC migration induced by COE, without suppression in CCE. In conclusion, these findings suggest that low protein levels of soluble VEGFr-1 may lead to corneal neovascularisation after COE sheet transplantation.
DOI 10.1136/bjo.2008.141580
PMID 19174402