熊切　順
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Surgery-assisted reproductive technology hybrid therapy: a reproductive procedure for an infertile woman of late reproductive age with multiple myomas.
Journal Formal name：The journal of obstetrics and gynaecology research
Abbreviation：J Obstet Gynaecol Res
ISSN code：13418076/13418076
Domestic / ForeginDomestic
Volume, Issue, Page 35(4),pp.827-31
Author and coauthor Kuroda Keiji, Takeuchi Hiroyuki, Kitade Mari, Kikuchi Iwaho, Kumakiri Jun, Kobayashi Yuko, Kobori Hiroyuki, Kuroda Masako, Itagaki Kazuko, Machida Mai, Takeda Satoru
Publication date 2009/08
Summary AIM:To produce a successful pregnancy in a 38-year-old infertile patient with relapsed myoma using a technique we refer to as 'surgery-assisted reproductive technology (ART) hybrid therapy' because it combines ART for cryopreservation of in vitro fertilized eggs with reproductive surgery.METHODS:A 38-year-old nulliparous woman who had undergone abdominal myomectomy and in whom magnetic resonance imaging showed multiple myomas was treated at our University-affiliated hospital and outpatient clinic. Blastocysts were cryopreserved during the preoperative period. Laparoscopic myomectomy was performed after preoperative treatment with a GnRH agonist. Ten months after the operation, the youngest cryopreserved blastocyst was transferred into the uterus and implanted successfully.RESULTS:Treatment resulted in successful implantation and pregnancy. In January 2008, the course of pregnancy had been uneventful and the patient gave birth to a male infant weighing 2998 grams by cesarean section at 37 weeks of gestation.CONCLUSION:We have treated eight patients using hybrid therapy with encouraging results, and we describe these cases herein briefly.
DOI 10.1111/j.1447-0756.2008.00977.x
PMID 19751354