コギソ トモミ   KOGISO Tomomi
  小木曽 智美
   所属   医学部 医学科(東京女子医科大学病院)
   職種   講師
論文種別 症例報告
言語種別 英語
査読の有無 査読あり
表題 Elevated α-Fetoprotein in the Absence of Carcinoma Caused by Relapse of Hepatitis C Viral Infection after Liver Transplantation.
掲載誌名 正式名:ACG case reports journal
略  称:ACG Case Rep J
ISSNコード:(2326-3253)2326-3253(Linking)
巻・号・頁 5,pp.e103
著者・共著者 KOGISO Tomomi,SAGAWA Takaomi,KOTERA Yoshihito,EGAWA Hiroto,YAMAMOTO Masakazu,TOKUSHIGE Katsutoshi
担当区分 筆頭著者,責任著者
発行年月 2018/12
概要 We report a rare case of marked elevation of α-fetoprotein in the absence of hepatocellular carcinoma caused by a relapse of hepatitis C virus (HCV) infection. A 58-year-old man underwent liver transplantation to treat hepatocellular carcinoma caused by HCV-related liver cirrhosis. The HCV was of genotype 2a, and the ribonucleic acid titer was >8.0 log IU/mL. Direct-acting antiviral drugs were prescribed for 12 weeks; however, the HCV infection relapsed after treatment had ended, and α-fetoprotein levels increased to 8,981 ng/mL. Imaging did not reveal any malignancies. The patient initiated interferon therapy, at which time AFP levels decreased, and the HCV was successfully cleared.
DOI 10.14309/crj.2018.103
PMID 30643846