イナイ シユンタ
  稲井 俊太
   所属   医学部 医学科(東京女子医科大学病院)
   職種   助教
論文種別 症例報告
言語種別 英語
査読の有無 査読あり
表題 Nodular fasciitis in the parotid gland: a case report and review of the literature.
掲載誌名 正式名:Diagnostic cytopathology
略  称:Diagn Cytopathol
ISSNコード:10970339/10970339
掲載区分国外
巻・号・頁 41(9),pp.829-833
著者・共著者 Peng Wei-Xia†, Kudo Mitsuhiro, Yamamoto Tetsushi, Inai Shunta, Fujii Takenori, Teduka Kiyoshi, Kawahara Kiyoko, Naito Zenya
発行年月 2013/09
概要 Nodular fasciitis (NF) is a benign, reactive lesion with a self-limiting process. Because NF is rare in the parotid gland and has many cytological similarities to other benign or malignant tumors, cytological misinterpretation is common. The patient, a 30-year-old woman, had a painless mass in her right parotid gland. Fine needle aspiration cytology (FNAC) was performed. Spindle cells with basophilic and well-demarcated cytoplasm were observed in a mucoid-like background. The mucoid-like substance was metachromatic and appeared to be the matrix of PA. Histopathologically, spindle-shaped cells with intervening birefringent mature collagen were arranged in short irregular bundles. Prominent mucoid-like matrixes as well as few infiltrating neutrophils and lymphocytes were found in the background. Lesional cells were positive for CD10 and β-catenin in the cytoplasm, but negative for cytokeratin, the S-100 protein, CD34, and neurofilament. Ultimately, this patient was diagnosed with NF. In FNAC of the parotid gland region, distinguishing NF from other real tumors is important for deciding treatment strategies.
DOI 10.1002/dc.22983
PMID 23749727