丸子 一朗
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Associate Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Misalignment between center of foveal avascular zone and center of foveal photoreceptors in eyes with idiopathic epiretinal membrane.
Journal Formal name:Retina (Philadelphia, Pa.)
Abbreviation:Retina
ISSN code:15392864/0275004X
Domestic / ForeginForegin
Volume, Issue, Page 41(8),pp.1635-1643
Author and coauthor Hasegawa Taiji, Kawaguchi Ai, Arakawa Hisaya, Maruko Ichiro, Iida Tomohiro
Publication date 2021/08
Summary PURPOSE:To determine the degree of misalignment between the center of foveal avascular zone (FAZ) and the center of foveal photoreceptors in eyes with an idiopathic epiretinal membrane (ERM).METHODS:We reviewed the medical records of 61 eyes with an idiopathic ERM. A 3×3 mm area centered on the fovea was scanned with optical coherence tomography angiography (OCTA) before and at 6 months after surgery. The center of FAZ and the center of foveal photoreceptors were detected by en face OCTA images and sequential OCT B-sections in the macular region. The presence or absence of ectopic inner foveal layers (EIFLs) was also evaluated.RESULTS:The mean distance from the center of foveal photoreceptors to the center of FAZ was 111.7 ± 106.8 μm in eyes with preoperative ERM. This distance was significantly correlated with the preoperative central foveal thickness (r = 0.33, P = 0.0104). Preoperatively, the EIFLs were present in 27 (44.3%) of 61 eyes. The foveal misalignment was greater in eyes with EIFLs than in those without EIFLs (158.6 ± 140.0 μm vs 74.4 ± 45.4 μm, P < 0.0003). At 6 months after ERM surgery, the foveal misalignment was significantly reduced to 73.7 ± 48.0 μm (P = 0.0018).CONCLUSION:Determining the degree of misalignment between center of FAZ and center of foveal photoreceptors might be a useful way to evaluate the degree of ERM traction.
DOI 10.1097/IAE.0000000000003064
PMID 33315819