丸子　一朗    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Associate Professor
Article types	Case report
Language	English
Peer review	Peer reviewed
Title	Retinal and choroidal circulation determined by optical coherence tomography angiography in patient with amyloidosis.
Journal	Formal name：BMJ case reports Abbreviation：BMJ Case Rep ISSN code：1757790X/1757790X
Domestic / Foregin	Foregin
Volume, Issue, Page	13(2),pp.118-120
Author and coauthor	Tei Masami†, Maruko Ichiro, Uchimura Eiko, Iida Tomohiro
Authorship	2nd author
Publication date	2019/02/21
Summary	A 43-year-old woman who was diagnosed with the cryopyrine-associated periodic syndrome (CAPS) with severe renal failure and heart failure due to amyloid accumulation was examined by swept source optical cohernce tomography (OCT) (SS-OCT; DRI-OCT, Topcon, Tokyo, Japan) and optical coherence tomography angiography (OCTA) (RTVue XR Avanti, Optovue, Fremont, CA). Her best-corrected visual acuity was 20/40 OD and 20/25 OS. A hyporeflective band of about 100 µm thickness was seen just inferior to the retinal pigment epithelium in the cross-sectional SS-OCT images, but the deeper choroidal structures were clearly visible. In the OCTA images, the density of the retinal capillaries in the superficial and deep capillary plexus slabs were reduced, and no signals of the choroidal capillary slab was detected after removing the projection artefacts. The accumulation of amyloid can cause a reduction of both the retinal and choroidal capillary circulations although the circulation in the larger vessels are preserved.
DOI	10.1136/bcr-2018-228479
PMID	30796071