HOSHINO Junichi
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Original article
Language English
Peer review Non peer reviewed
Title Autopsy of a 45-year-old Man with Liver Failure Due to Polycystic Liver Disease
Journal Formal name:Internal medicine (Tokyo, Japan)
Abbreviation:Intern Med
ISSN code:13497235/09182918
Domestic / ForeginForegin
Volume, Issue, Page pp.Online
Author and coauthor Mizuta Masato, Sekine Akinari, Suwabe Tatsuya, Hoshino Junichi, Yamanouchi Masayuki, Mizuno Hiroki, Ikuma Daisuke, Hasegawa Eiko, Oba Yuki, Kono Kei, Kinowaki Keiichi, Ohashi Kenichi, Sawa Naoki, Ubara Yoshifumi
Publication date 2024/02/01
Summary A 37-year-old man with autosomal polycystic kidney disease (ADPKD) was admitted to our hospital with a liver volume of 8,000 cm3. Hepatic arterial embolization was performed using a microcoil but was ineffective. Eight years later, the hepatomegaly progressed to liver failure and death. At autopsy, the liver weighed 21.5 kg, and the entire liver had been replaced by cysts; in the few remaining areas of liver parenchyma, microscopic, small cysts of various sizes and fibrosis were evident, with only a few normal hepatocytes observed. Hepatic arterial branches developed; however, the portal vein could not be observed.
DOI 10.2169/internalmedicine.2485-23
PMID 38296484