HOSHINO Junichi
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Case report
Language English
Peer review Peer reviewed
Title Crescentic Glomerulonephritis with Fibrinoid Vasculitis after Administration of Influenza Vaccine.
Journal Formal name:Internal medicine (Tokyo, Japan)
Abbreviation:Intern Med
ISSN code:13497235/09182918
Domestic / ForeginForegin
Volume, Issue, Page 62(7),pp.1077-1080
Author and coauthor Hara Risa, Hasegawa Eiko, Inoue Noriko, Sekine Akinari, Tanaka Kiho, Ikuma Daisuke, Mizuno Hiroki, Oba Yuki, Yamanouchi Masayuki, Suwabe Tatsuya, Sawa Naoki, Kono Kei, Kinowaki Keiichi, Ohashi Kenichi, Ubara Yoshifumi, Hoshino Junichi
Authorship Last author,Corresponding author
Publication date 2023/04/01
Summary A 66-year-old man was admitted to our hospital because of a low-grade fever and arthralgia. The symptoms started on the third day after influenza vaccine administration and persisted for two months. Serum creatinine was 1.0 mg/dL; C-reactive protein, 16.1 mg/dL; and myeloperoxidase antineutrophil cytoplasmic antibodies (MPO-ANCA), 4,170 IU/mL. A kidney biopsy showed crescentic glomerulonephritis with fibrinoid necrosis of small arteries. Microscopic polyangiitis was diagnosed. After five months of steroid pulse therapy and rituximab administration, the patient entered remission. There have been very few reports of this condition after influenza vaccine administration.
DOI 10.2169/internalmedicine.9410-22
PMID 36070955