ホシノ ジユンイチ   HOSHINO Junichi
  星野 純一
   所属   医学部 医学科(東京女子医科大学病院)
   職種   教授・基幹分野長
論文種別 原著
言語種別 英語
査読の有無 査読なし
表題 Syphilis-associated membranous nephropathy successfully treated with amoxicillin.
掲載誌名 正式名:Clinical nephrology
略  称:Clin Nephrol
ISSNコード:03010430/03010430
掲載区分国外
巻・号・頁 96(5),pp.297-301
著者・共著者 Hazue Ryo, Ueno Toshiharu, Nozaki Hiroyuki, Kinowaki Keiichi, Ohashi Kenichi, Hoshino Junichi, Sawa Naoki, Ubara Yoshifumi
発行年月 2021/11
概要 A 33-year-old Japanese man with no significant past medical history was admitted to our hospital for evaluation of weight gain and pitting edema. A laboratory test confirmed nephrotic-range proteinuria. Renal biopsy showed subepithelial deposits, and membranous nephropathy (MN) was diagnosed. Closer examination clarified an active syphilis infection. After renal biopsy, we prescribed amoxicillin for 8 weeks to treat the syphilis infection. Three weeks later, the patient's proteinuria dramatically decreased. This case is of interest because syphilis can become a cause of acute-onset MN in younger adults, and the incidence of syphilis is increasing in Japan.
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DOI 10.5414/CN110586
PMID 34448699