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勝又 康弘
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Assistant Professor |
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| Article types | Original article |
| Language | English |
| Peer review | Non peer reviewed |
| Title | Interstitial Lung Disease with ANCA-associated Vasculitis. |
| Journal | Formal name：Clinical medicine insights. Circulatory, respiratory and pulmonary medicine Abbreviation：Clin Med Insights Circ Respir Pulm Med ISSN code：(1179-5484)1179-5484(Linking) |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 9(Suppl 1),pp.51-6 |
| Author and coauthor | Katsumata Yasuhiro†, Kawaguchi Yasushi*, Yamanaka Hisashi |
| Authorship | Lead author |
| Publication date | 2015 |
| Summary | The association between interstitial lung disease (ILD) and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), particularly microscopic polyangiitis (MPA), has been described in a number of case reports and case series reports in the last 2 decades. In addition, patients with pulmonary fibrosis and ANCA positivity but without other manifestations of systemic vasculitis have also been reported. Pulmonary fibrosis was clinically manifested at the time of diagnosis in the majority of AAV patients that developed this condition. Moreover, ANCA-positive conversion occurs in patients initially diagnosed with idiopathic pulmonary fibrosis, and as a result, other manifestations of systemic vasculitis develop in some of these patients. There is significant predominance of myeloperoxidase (MPO)-ANCA and MPA in patients with AAV and ILD. Radiological and pathological findings generally demonstrate usual interstitial pneumonia (pattern) in the lungs of these patients. In most studies, AAV patients with ILD have a worse prognosis than those without it. |
| DOI | 10.4137/CCRPM.S23314 |
| PMID | 26448696 |