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HARADA Gen
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Assistant Professor |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Skeletal muscle index determined by bioelectrical impedance analysis is a determinant of exercise capacity and a prognostic predictor in patients with congenital heart disease. |
| Journal | Formal name：Journal of cardiology Abbreviation：J Cardiol ISSN code：09145087/18764738 |
| Domestic / Foregin | Domestic |
| Publisher | Elsevier publishes on behalf of the Japanese College of Cardiology |
| Volume, Issue, Page | pp.in press |
| Author and coauthor | SATO Masaki†, INAI Kei*, ASAGAI Seiji, HARADA Gen, SHIMADA Eriko, SUGIYAMA Hisashi |
| Publication date | 2020/05 |
| Summary | RESULTS:The multivariate analysis revealed a significant correlation between peakVO2 and EI (r = -0.55) and peakVO2 and SMI (r = 0.49). The receiver operating characteristic curve analysis showed that the EI cut-off for peakVO2 <20 ml/kg/min was 0.386 [area under the curve (AUC), 0.77; sensitivity, 0.67; specificity 0.76], and the SMI cut-off was 7.6 kg/m2 (AUC, 0.78; sensitivity, 0.76; specificity 0.75). Compared with patients who had biventricular morphology, patients with single ventricular morphology had a higher EI (mean, 0.381 vs. 0.387, respectively) and lower SMI (8.5 vs. 7.7, respectively), resulting in a lower peakVO2 (27.1 vs. 20.8, respectively). The Kaplan-Meier analysis showed that a low SMI was associated with an increased risk of future heart failure-related admissions.
CONCLUSIONS:SMI determined by BIA is a determinant of exercise capacity and can be used as a prognostic predictor in patients with CHD. |
| DOI | 10.1016/j.jjcc.2020.04.011 |
| PMID | 32439338 |