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末吉 亮
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Assistant Professor |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | In prenatally diagnosed CPAM, does the affected lobe influence the timing of symptom onset? |
| Journal | Formal name：Pediatric surgery international Abbreviation：Pediatr Surg Int ISSN code：14379813/01790358 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 35(5),pp.559-563 |
| Author and coauthor | Sueyoshi R†, Shibuya S, Ochi T, Okawada M, Miyano G, Koga H, Lane G J, Yamataka A |
| Authorship | Lead author |
| Publication date | 2019/05 |
| Summary | PURPOSE:We investigated the relationship between the affected lobe and symptom onset in prenatally diagnosed congenital pulmonary airway malformation (CPAM).METHODS:53 CPAM patients diagnosed prenatally were reviewed retrospectively by creating 2 groups according to symptom onset. Group Sneo: (symptomatic during the neonatal period; n = 13) and group S > neo: (symptomatic after the neonatal period; n = 40) were compared for type of CPAM, affected lobes, types of symptoms/infections, treatment, duration of follow-up, and histopathology. Requirement for surgery (Sx) was then used to create three subgroups: Sneo + Sx, S > neo + Sx, and Sx-.RESULTS:Some cases had multiple affected lobes. In Sneo, symptoms developed in 55.6%, 50.0%, 0%, 0%, and 36.8% of right upper lobes (RUL), right middle lobes (RML), right lower lobes (RLL), left upper lobes (LUL), and left lower lobes (LLL) diagnosed with CPAM, prenatally. In S > neo, symptoms developed in 0%, 0%, 6.3%, 55.6%, and 33.3% of RUL, RML, RLL, LUL, and LLL diagnosed with CPAM, prenatally.CONCLUSION:In prenatally diagnosed CPAM, RUL and RML lesions are more likely to become symptomatic in neonates, and LUL lesions in infants. Surgery is recommended before the onset of respiratory infections after 1 year of age. |
| DOI | 10.1007/s00383-019-04460-x |
| PMID | 30778700 |