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坂口 勝久
Department Research Institutes and Facilities, Research Institutes and Facilities Position |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | The potential of cell sheet technique on the development of hepatocellular carcinoma in rat models. |
| Journal | Formal name：PloS one Abbreviation：PLoS One ISSN code：(1932-6203)1932-6203(Linking) |
| Volume, Issue, Page | 12(8),pp.e0184004 |
| Author and coauthor | Alshareeda Alaa T†*, Sakaguchi Katsuhisa, Abumaree Mohammed, Mohd Zin Nur Khatijah, Shimizu Tatsuya |
| Authorship | 2nd author |
| Publication date | 2017/08 |
| Summary | Since this is a novel study to induce liver tumour in rats using hepatocellular carcinoma sheet and stromal cells, the data obtained suggest that cell sheet is a fast and easy technique to develop HCC models as well as UC-MSCs have therapeutic potential for liver diseases. Additionally, the data procured indicates that stromal cells enhanced the fabrication of HepG2 cell sheets. This provides the foundation for future research using stromal cells in preclinical and clinical investigations. |
| DOI | 10.1371/journal.pone.0184004 |
| PMID | 28850615 |