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井口 成一
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | Higher efficacy of direct hemoperfusion using coated activated-charcoal column for disopyramide poisoning: A case report. |
| Journal | Formal name：Medicine Abbreviation：Medicine (Baltimore) ISSN code：(1536-5964)0025-7974(Linking) |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 96(49),pp.e8755 |
| Author and coauthor | Iguchi Shigekazu, Yamaguchi Naotaka, Takami Hiroki, Komatsu Takayuki, Ookubo Hirokazu, Sekii Hajime, Inoue Kenji, Okazaki Shinya, Okai Iwao, Maruyama Sonomi, Nomura Tomohisa, Sugita Manabu |
| Authorship | Lead author,Corresponding author |
| Publication date | 2017/12 |
| Summary | Because disopyramide has low molecular weight and a small distribution volume, blood purification is considered to be the most effective therapy. We selected direct hemoperfusion for relatively high protein-binding rate. In fact, clinical status was dramatically improved, and the calculated half-life of the direct hemoperfusion phase was the shortest of all phases. In cases of severe or life-threatening disopyramide poisoning, blood purification therapy including direct hemoperfusion using a coated activated-charcoal column should be performed. |
| DOI | 10.1097/MD.0000000000008755 |
| PMID | 29245231 |