井口 成一
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position  
Article types Case report
Language English
Peer review Peer reviewed
Title Higher efficacy of direct hemoperfusion using coated activated-charcoal column for disopyramide poisoning: A case report.
Journal Formal name:Medicine
Abbreviation:Medicine (Baltimore)
ISSN code:(1536-5964)0025-7974(Linking)
Domestic / ForeginForegin
Volume, Issue, Page 96(49),e8755頁
Author and coauthor Iguchi Shigekazu, Yamaguchi Naotaka, Takami Hiroki, Komatsu Takayuki, Ookubo Hirokazu, Sekii Hajime, Inoue Kenji, Okazaki Shinya, Okai Iwao, Maruyama Sonomi, Nomura Tomohisa, Sugita Manabu
Publication date 2017/12
Summary Because disopyramide has low molecular weight and a small distribution volume, blood purification is considered to be the most effective therapy. We selected direct hemoperfusion for relatively high protein-binding rate. In fact, clinical status was dramatically improved, and the calculated half-life of the direct hemoperfusion phase was the shortest of all phases. In cases of severe or life-threatening disopyramide poisoning, blood purification therapy including direct hemoperfusion using a coated activated-charcoal column should be performed.
DOI 10.1097/MD.0000000000008755
PMID 29245231