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OMORI Teppei
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position |
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| Article types | Original article |
| Language | English |
| Peer review | Non peer reviewed |
| Title | Nationwide multicenter study on adverse events associated with a patency capsule: Additional survey of appropriate use of patency capsule study |
| Journal | Formal name：Journal of gastroenterology and hepatology Abbreviation：J Gastroenterol Hepatol ISSN code：14401746/08159319 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 39(2),pp.337-345 |
| Author and coauthor | OMORI Teppei,OHMIYA Naoki,WATANABE Kenji,HIRAI Fumihito,NAKAMURA Masanao,KITAMURA Kazuya,OZEKI Keiji,OKA Shiro,KAWANO Seiji,HANDA Osamu,KAWAI Mikio,NINOMIYA Kazeo,SAGAWA Tamotsu,WAKAMATSU Takahiro,ARAI Akihiro,KOIKE Yuji,KATO Shingo,HASHIMOTO Shinichi,MANNAMI Tomohiko,NAKAJI Konosuke,TANAKA Shinji,MATSUI Toshiyuki |
| Authorship | Lead author |
| Publication date | 2024/02 |
| Summary | BACKGROUND AND AIM:The PillCam patency capsule (PC) without a radio frequency identification tag was released to preclude retention of the small bowel capsule endoscope (CE) in Japan in 2012. We conducted a multicenter study to determine tag-less PC-related adverse events (AEs).METHODS:We first conducted a retrospective survey using a standardized data collection sheet for the clinical characteristics of PC-related AEs among 1096 patients collected in a prospective survey conducted between January 2013 and May 2014 (Cohort 1). Next, we retrospectively investigated additional AEs that occurred before and after Cohort 1 within the period June 2012 and December 2014 among 1482 patients (Cohort 2).RESULTS:Of the 2578 patients who underwent PC examinations from both cohorts, 74 AEs occurred among 61 patients (2.37%). The main AEs were residual parylene coating in 25 events (0.97%), PC-induced small bowel obstruction, suspicious of impaction, in 23 events (0.89%), and CE retention even after patency confirmation in 10 events (0.39%). Residual parylene coating was significantly associated with Crohn's disease (P < 0.01). Small bowel obstruction was significantly associated with physicians with less than 1 year of experience handling the PC and previous history of postprandial abdominal pain (P < 0.01 and P < 0.03, respectively). CE retention was ascribed to erroneous judgment of PC localization in all cases.CONCLUSIONS:This large-scale multicenter study provides evidence supporting the safety and efficiency of a PC to preclude CE retention. Accurate PC localization in patients without excretion and confirmation of previous history of postprandial abdominal pain before PC examinations is warranted (UMIN000010513). |
| DOI | 10.1111/jgh.16365 |
| PMID | 37842961 |