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OMORI Teppei
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position |
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| Article types | Original article |
| Language | English |
| Peer review | Non peer reviewed |
| Title | Efficacy of Calcineurin Inhibitors for Induction of Remission in Intestinal Behçet's Disease. |
| Journal | Formal name：Crohn's & colitis 360 Abbreviation：Crohns Colitis 360 ISSN code：2631827X/2631827X |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 4(3),pp.otac017 |
| Author and coauthor | KAWAGUCHI Takaaki, FUKATA Masayuki, OMORI Teppei, KIYOHARA Hiroki, SUGIMOTO Shinya, NANKI Kosaku, SUJINO Tomohisa, MIKAMI Yohei, KANAI Takanori |
| Publication date | 2022/07 |
| Summary | BACKGROUND:The efficacy of calcineurin inhibitors (CNIs) for induction of remission in intestinal Behçet's disease (intestinal BD) has not been explored.METHODS:A multicenter retrospective case series study of patients with active intestinal BD treated with CNIs (cyclosporin and tacrolimus) was conducted.RESULTS:Of 16 patients, 12 (75%) showed a clinical response and 5 (31.3%) achieved clinical remission after 2 weeks of CNI treatment. Similar efficacy of CNIs was observed even in 7 patients refractory to antitumor necrosis factor-alpha therapies. Endoscopic improvement was observed in 11 of 12 patients.CONCLUSIONS:CNIs may be promising treatment options for refractory intestinal BD. |
| DOI | 10.1093/crocol/otac017 |
| PMID | 36777415 |