HORI Sayaka
   Department   School of Medicine, School of Medicine
   Position   Assistant Professor
Article types Other
Language English
Peer review Peer reviewed
Title Expression of two microRNAs, ame-mir-276 and -1000, in the adult honeybee (Apis mellifera) brain.
Journal Formal name:Apidologie
Domestic / ForeginForegin
Volume, Issue, Page 42,89-102頁
Author and coauthor Hori Sayaka, Kaneko Kumi, Saito TH, Takeuchi Hideaki, Kubo Tubo
Publication date 2010/07
Summary To identify candidate microRNAs involved in post-transcriptional regulation of brain (region)-selective gene expression in the adult honeybee brain, we isolated eight microRNAs: seven known microRNAs, ame-mir-2-1, −8, 13a, −34, −276, −317, −1000, and one novel one, named mir-hbd, that has significant sequence similarity with the Drosophila dme-mir-11. Among them, ame-mir-1000 and −276 were expressed in a brain-selective and -preferential manner, respectively, in workers and drones. In particular, ame-mir-276-expression was enriched in the optic lobes and in the small type-Kenyon cells of the mushroom bodies in the nurse bee, forager, queen, and drone brains. Almost all predicted targets of amemir-1000 and −276 encode neural function related genes, suggesting the involvement in neural function of both microRNAs.
DOI 10.1051/apido/2010032