ナカジマ　ヨシユキ   NAKAJIMA Yoshiyuki   中島　義之    所属   医学部 医学科（附属八千代医療センター）    職種   准教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Evaluation of creatine kinase, lactate dehydrogenase, and amylase concentrations in umbilical blood of preterm infants after long-term tocolysis.
掲載誌名	正式名：Obstetrics and gynecology international 略　 称：Obstet Gynecol Int ISSNコード：16879589/16879597
掲載区分	国外
巻・号・頁	2014,pp.278379
著者・共著者	Nakajima Yoshiyuki, Masaoka Naoki
発行年月	2014
概要	Creatine kinase (CK), lactate dehydrogenase (LDH), and amylase levels of preterm infants following long-term tocolysis in pregnant women are limited. The objective of this study was to determine if the tocolytic therapy affects CK, LDH, and amylase levels in the umbilical blood. This study included 215 preterm infants born to women treated with and without ritodrine hydrochloride. CK, LDH, and amylase levels in the umbilical blood at delivery were determined. Infants were divided according to the ritodrine tocolysis, as follows: Group A (n = 91), not exposed to ritodrine; Group B (n = 44), IV ritodrine for <1 week; Group C (n = 80), IV ritodrine for ≥1 week. The CK concentration in cord blood of Group C (198.8 ± 14.2 IU/L) was significantly higher in comparison with Group A (155.0 ± 7.3 IU/L, P < 0.05). There was no significant difference in LDH and amylase levels in the three groups. The CK significantly correlated with gestational age (r = 0.42, P < 0.01) and birth weight (r = 0.38, P < 0.01). LDH and amylase levels did not change with gestational age nor birth weight. In conclusion, long-term ritodrine tocolysis leads to increased umbilical blood CK level.
DOI	10.1155/2014/278379
PMID	24693289