水主川 純
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Case report
Language English
Peer review Peer reviewed
Title Peripartum heart failure caused by left ventricular diastolic dysfunction: a case report.
Journal Formal name:Acta obstetricia et gynecologica Scandinavica
Abbreviation:Acta Obstet Gynecol Scand
ISSN code:16000412/00016349
Domestic / ForeginForegin
Volume, Issue, Page 93(8),pp.835-8
Author and coauthor Kakogawa Jun, Nako Takafumi, Igarashi Suguru, Nakamura Shin, Tanaka Mamoru
Authorship Lead author,Corresponding author
Publication date 2014/08
Summary Peripartum cardiomyopathy is a rare but potentially life-threatening condition. The current definition of peripartum cardiomyopathy only includes patients with systolic dysfunction. We describe a 25-year-old nulligravid patient with heart failure, i.e. left ventricular diastolic dysfunction with preserved systolic dysfunction during the third trimester of pregnancy. She complained of dyspnea and was referred to our hospital at 31 weeks of gestation. The patient met the clinical criteria for peripartum cardiomyopathy with the exception of systolic dysfunction. Brain-type natriuretic peptide levels peaked at 1447 pg/dL. The patient responded to therapy for heart failure and showed resolution of her diastolic dysfunction by 1 month postpartum. The case demonstrated the important role of diastolic dysfunction in peripartum heart failure and the possibility of clarifying the pathophysiology of peripartum cardiomyopathy by evaluating diastolic function. Further investigations are needed to provide evidence regarding the clinical role of diastolic dysfunction in peripartum heart failure.
DOI 10.1111/aogs.12408
PMID 24797205