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水主川 純
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor and Division head |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | Prolonged fetal bradycardia as the presenting clinical sign in congenital syphilis complicated by necrotizing funisitis: a case report. |
| Journal | Formal name：ISRN obstetrics and gynecology Abbreviation：ISRN Obstet Gynecol ISSN code：20904444/20904436 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 2011,pp.320246 |
| Author and coauthor | Kakogawa Jun, Sadatsuki Miyuki, Masuya Norio, Gomibuchi Hideto, Minoura Shigeki, Hoshimoto Kazuhusa |
| Authorship | Lead author,Corresponding author |
| Publication date | 2011 |
| Summary | Syphilis remains a serious cause of neonatal morbidity and mortality worldwide. In this paper, we describe a case of congenital syphilis that was fully supported by abnormal fetal heart rate patterns and placental histopathological evidence. A 24-year-old para 4 woman, who did not attend antenatal care, was admitted to our hospital with a complaint of abdominal discomfort at an estimated 31-week gestation. Fetal heart rate monitoring showed prolonged bradycardia. A neonate weighting 1,423 g with severe birth asphyxia was immediately delivered by cesarean section. Following delivery, the mother and the neonate were diagnosed with syphilis. Histopathological examination confirmed severe chorioamnionitis and necrotizing funisitis with numerous Treponema pallidum. Conclusions. Challenges in establishing the diagnosis of necrotizing funisitis are essential for optimal management of a fetus with a systemic inflammatory response in utero. |
| DOI | 10.5402/2011/320246 |
| PMID | 21766037 |