カコガワ　ジユン   水主川　純    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Noninvasive monitoring of placental oxygenation by near-infrared spectroscopy.
掲載誌名	正式名：American journal of perinatology 略　 称：Am J Perinatol ISSNコード：10988785/07351631
掲載区分	国外
巻・号・頁	27(6),pp.463-8
著者・共著者	Kakogawa Jun, Sumimoto Kazuhiro, Kawamura Takakazu, Minoura Shigeki, Kanayama Naohiro
担当区分	筆頭著者,責任著者
発行年月	2010/06
概要	We evaluated the clinical usefulness of near-infrared spectroscopic quantitative measurement of placental oxygenation for the noninvasive estimation of uteroplacental function in pregnant women. We performed a prospective, observational clinical study. Women without complications (N = 15), women with threatened preterm delivery (TPD; N = 6), and women with intrauterine fetal growth restriction (IUGR; N = 6) were enrolled. Measurements of placental tissue oxygenation index (TOI) using the NIRO-300 (Hamamatsu Photonics, Hamamatsu City, Japan) were recorded. Mean TOI was 72.3 +/- 5.3% in women without complications, 72.9 +/- 5.6% in pregnant women with TPD, and 78.7 +/- 3.0% in pregnant women with IUGR. Mean TOI in pregnant women with IUGR was significantly higher than that of the other two groups (P < 0.05). In the IUGR group, although gestational age at measurement on admission was less than that made during hospitalization (P < 0.05), there were no differences in the TOI in relation to gestational age at measurement. Higher TOIs in pregnant women suggest decreased placental function. Monitoring the TOI by near-infrared spectroscopic quantitative measurement may have a high potential for clinical application, particularly in prenatal management.
DOI	10.1055/s-0030-1247600
PMID	20119892