水主川　純
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor and Division head
Article types Original article
Language English
Peer review Peer reviewed
Title Measurement of placental oxygenation by transabdominal near-infrared spectroscopy.
Journal Formal name：American journal of perinatology
Abbreviation：Am J Perinatol
ISSN code：07351631/07351631
Domestic / ForeginForegin
Volume, Issue, Page 24(3),pp.161-6
Author and coauthor Kawamura Takakazu, Kakogawa Jun, Takeuchi Yasutaka, Takani Satoko, Kimura Satoshi, Nishiguchi Tomizou, Sugimura Motoi, Sumimoto Kazuhiro, Kanayama Naohiro
Authorship 2nd author
Publication date 2007/03
Summary The uteroplacental circulation in the placenta can have a major impact on the fetus. Near infrared spectroscopy (NIRS) is the noninvasive method of measuring changes in blood volumes and oxygen concentrations in living tissue. The purpose of this study is to monitor changes in placental tissue oxygen index (TOI) levels, in patients with intrauterine fetal growth restriction during pregnancy, using NIRS. We measured placental TOI values of 15 normal pregnant woman and 15 patients with intrauterine growth restriction admitted to our hospital. The placenta was assessed by ultrasound examination and NIRS was performed on all patients. The TOI values of the IUGR group when hospitalized was 78.6 +/- 1.6 (SD). This value was significantly higher than that of the controls (78.6 +/- 1.6 [SD] versus 70.2 +/- 0.4 [SD]). And the TOI values of the IUGR group, when measured before delivery, were 77.8 +/- 1.6 (SD). The TOI values of the IUGR group before delivery were significantly higher than those of the control group (77.8 +/- 1.6 [SD] versus 70.3 +/- 0.4 [SD]). We propose that NIRS is a candidate, noninvasive method for assessing placental oxygen dynamics on a real-time basis. In the near future it may contribute to perinatal medical practice.
DOI 10.1055/s-2006-958155
PMID 17304421