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NONAKA Kouichi
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor |
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| Article types | Case report |
| Language | English |
| Peer review | Non peer reviewed |
| Title | Endoscopic Image 2 Hours after PuraStat® Application: A Case of Achieving Hemostasis Using PuraStat® for Postgastric Lesion Biopsy Bleeding after Hemostatic Clips Failed. |
| Journal | Formal name：Case reports in gastrointestinal medicine Abbreviation：Case Rep Gastrointest Med ISSN code：20906528 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 2023,pp.5620348 |
| Author and coauthor | MISUMI Yoshitsugu, NONAKA Kouichi, KISHINO Maiko |
| Authorship | 2nd author |
| Publication date | 2023/07 |
| Summary | PuraStat® (3D Matrix, Tokyo, Japan) is a novel, self-assembling peptide hemostatic hydrogel that can be used endoscopically. Hemostasis can be physically obtained by covering bleeding points; however, there are no reports of how long PuraStat remains in the upper gastrointestinal tract. Herein, we report a case wherein esophagogastroduodenoscopy (EGD) was performed 2 hours after PuraStat application. A 73-year-old man underwent EGD for evaluation of lesions in the posterior wall of the stomach. A biopsy was then performed on the gastric lesions; however, massive bleeding occurred. A hemostatic clip was used to stop bleeding but failed; primary hemostasis was obtained by applying PuraStat. EGD performed 2 hours later to determine whether the patient could be discharged revealed that the white-turning PuraStat gel remained firmly in the applied area, confirming complete hemostasis. PuraStat is a hemostatic agent capable of physical hemostasis that reliably remains in the stomach even after a few hours of use and, thus, may replace some conventional hemostasis methods. |
| DOI | 10.1155/2023/5620348 |
| PMID | 37547442 |