野中 康一
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor
Article types Case report
Language English
Peer review Non peer reviewed
Title A case of reflux laryngitis after iodine staining for esophageal squamous cell carcinoma
Journal Formal name:DEN open
Abbreviation:DEN Open
ISSN code:26924609/26924609
Domestic / ForeginDomestic
Volume, Issue, Page 4(1),pp.e306
Author and coauthor YATSUJI Sho, MISUMI Yoshitsugu, TAMIYA Akiko, NONAKA Kouichi
Authorship Last author
Publication date 2024/04
Summary Iodine staining allows for clear visualization of the lesion boundaries of esophageal squamous cell carcinoma and is used as the gold standard for detecting and diagnosing the extent of the cancer. Heartburn and retrosternal pain are known side effects; however, no reports of pharyngitis or laryngitis exist. Therefore, we present a case of laryngitis caused by iodine reflux. An 80-year-old female patient underwent endoscopic submucosal dissection for superficial esophageal cancer. During the operation, a reflux of the iodine used for diagnosing the extent of the lesion occurred, and she experienced laryngitis accompanied by hoarseness postoperatively, which improved with steroid administration. Laryngitis due to iodine reflux may cause airway stenosis, and preventing reflux requires anterograde application of iodine and spraying iodine as gently and locally as possible.
DOI 10.1002/deo2.306
PMID 37900616