ワカバヤシ ヒデタカ   Wakabayashi Hidetaka
  若林 秀隆
   所属   医学部 医学科(東京女子医科大学病院)
   職種   教授・基幹分野長
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Relationship of body mass index on activities of daily living in hospitalized patients with chronic obstructive pulmonary disease.
掲載誌名 正式名:Respiratory medicine and research
略  称:Respir Med Res
ISSNコード:25900412/25900412
掲載区分国外
巻・号・頁 81,pp.100899
著者・共著者 Tomohara-Ichishima Hitomi, Wakabayashi Hidetaka, Maeda Keisuke, Nishioka Shinta, Momosaki Ryo
担当区分 2nd著者
発行年月 2022/05
概要 BACKGROUND:Weight loss and low lean body mass in patients with chronic obstructive pulmonary disease (COPD) are associated with increased mortality; however, the association between body mass index (BMI) and physical ability remains undetermined. We aimed to investigate the effect of BMI on activities of daily living (ADL) in hospitalized patients with COPD.METHODS:We used the Japan Medical Data Center's hospital-based database to extract data on hospitalized patients aged ≥ 20 years admitted for COPD between April 2014 and December 2018. The primary outcome was the presence or absence of deterioration in the Barthel Index score for ADLs at discharge compared with that at admission. Secondary outcomes were the length of hospital stay, readmission within 30 days, and the number of drugs administered on admission.RESULTS:We identified 6529 patients with COPD from the Diagnosis Procedure Combination database, of which 3476 were analyzed (excluded: n = 5, ages < 20 years; n = 3048, missing entries). Barthel Index scores tended to decline in patients with BMI < 18.5 kg/m2 (odds ratio, OR: 2.030, p < 0.001) and Hugh-Jones grade 4 (OR: 1.79, p = 0.05) and grade 5 (OR: 2.15, p = 0.01), but not in the obese group (p = 0.598). The low-weight group had a significantly longer hospital stay (p < 0.001) at 14 (8-25) days with greater readmissions within 30 days (6.3%, p < 0.001).CONCLUSION:Low BMI is associated with lower Barthel Index scores, longer hospital stays, requiring readmissions within 30 days of discharge.
DOI 10.1016/j.resmer.2022.100899
PMID 35523042