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Wakabayashi Hidetaka
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor and Division head |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Predictive Validity of Body Mass Index Cut-off Values Used in the GLIM Criteria for discriminating Severe and Moderate Malnutrition Based on In-Patients With Pneumonia in Asian Populations. |
| Journal | Formal name：JPEN. Journal of parenteral and enteral nutrition Abbreviation：JPEN J Parenter Enteral Nutr ISSN code：19412444/01486071 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 36,pp.1-11 |
| Author and coauthor | Shimizu Akio, Maeda Keisuke, Wakabayashi Hidetaka, Nishioka Shinta, Nagano Ayano, Kayashita Jun, Fujishima Ichiro, Momosaki Ryo |
| Publication date | 2020/07 |
| Summary | BACKGROUND:This study aimed to investigate the predictive validity of the previously reported body mass index (BMI) cut-off values of the Global Leadership Initiative on Malnutrition (GLIM) criteria for patients with pneumonia in Asian populations using a nationwide registry database.METHODS:The study included 26,098 (2,282 patients aged <70 years and 23,784 patients aged ≥70 years) patients with pneumonia aged ≥65 years who were enrolled in the Japan Medical Data Center database between April 2014 and December 2018. Malnutrition was diagnosed using the GLIM criteria, and the severity of malnutrition was diagnosed on using a BMI cut-off value of <17.0 kg/m2 and <17.8 kg/m2 for patients aged <70 years and ≥70 years, respectively. Multivariate analysis was performed to determine whether the severity of malnutrition based on BMI was associated with poor clinical outcomes such as 30-day in-hospital mortality, length of hospital stay (LOS), and 30-day readmission.RESULTS:A total of 14.7% and 24.1% of patients aged <70 years and ≥70 years, respectively, experienced severe malnutrition. Severe malnutrition was indsependently associated with 30-day in-hospital mortality (hazard ratio [HR], 1.19; 95% confidence interval [CI], 1.05-1.34), prolonged LOS (coefficient, 5.13; 95%CI, 4.31-5.94), and 30-day readmission (HR, 2.28; 95%CI, 1.89-2.75) in patients aged ≥70 years; however, only prolonged LOS was independently associated with patients aged <70 years (coefficient, 3.27; 95%CI, -0.24-6.78).CONCLUSION:The BMI cut-off values might be valid for patients with pneumonia aged ≥70 years in Asian populations. Further investigation is required to validate the cut-off value for older adults aged <70 years. <PE-FRONTEND> This article is protected by copyright. All rights reserved. |
| DOI | 10.1002/jpen.1959 |
| PMID | 32677042 |