種田 積子
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Associate Professor |
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Article types | Original article |
Language | English |
Peer review | Peer reviewed |
Title | Up-regulation of extracellular matrix proteoglycans and collagen type I in human crescentic glomerulonephritis. |
Journal | Formal name:Kidney international Abbreviation:Kidney Int ISSN code:(0085-2538)0085-2538(Linking) |
Domestic / Foregin | Foregin |
Volume, Issue, Page | 59(2),pp.532-42 |
Author and coauthor | Stokes M B, Hudkins K L, Zaharia V, Taneda S, Alpers C E |
Publication date | 2001/02 |
Summary | The temporal and spatial patterns of expression demonstrated in this study provide evidence to support pathogenic roles for PG in the evolution of CGN. Based on known biological properties of this molecule, versican may facilitate migration of cells in developing crescents. Decorin and biglycan may contribute to progression of CGN, perhaps via interactions with collagen type I in the remodeled extracellular matrix. |
DOI | 10.1046/j.1523-1755.2001.059002532.x |
PMID | 11168935 |