Ikari Katsunori
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Professor
Article types Original article
Language English
Peer review Peer reviewed
Title A case of Castleman's disease associated with diffuse idiopathic skeletal hyperostosis and ossification of the posterior longitudinal ligament of the spine.
Journal Formal name:Modern rheumatology
Abbreviation:Mod Rheumatol
ISSN code:(1439-7595)1439-7595(Linking)
Volume, Issue, Page 17(5),pp.418-421
Author and coauthor KOBAYASHI Shu, MOMOHARA Shigeki, IKARI Katsunori, MOCHIDUKI Takeshi, KAWAMURA Koichiro, TSUKAHARA So, NISHIMOTO Kazumasa, OKAMOTO Hiroshi, TOMATSU Taisuke
Publication date 2007
Summary Castleman's disease (CD), diffuse idiopathic skeletal hyperostosis (DISH), and ossification of the posterior longitudinal ligament of the spine (OPLL) are three different entities. Castleman's disease displaying a variety of calcifications in the abdomen and/or pelvis has been reported in some papers. However, there were no reports suggesting an association between CD and ossification/calcification in spine and joints. So far, there has been no case report regarding the coexistence of these diseases in the literature. Herein, we detail a 75-year-old man suffering from CD who demonstrated the features of DISH with coexisting features of OPLL. The cardinal symptoms such as fatigue, high fever, and swollen glands in this case were reduced by corticosteroid therapy. However, it is possible to produce actual symptoms of ossifying/calcified diathesis of entheses and ligaments as a consequence, like the pathology of calcification found in the region of the spleen. In this paper, we describe this patient in order to discuss the association of these diseases.
DOI 10.1007/s10165-007-0599-2
PMID 17929136