OSHIBUCHI Hidehiro
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Associate Professor
Article types Original article
Language English
Peer review Peer reviewed
Presence of invitation Invited paper
Title Guidelines for Diagnosis and Treatment of Depression in Older Adults: a Report from the Japanese Society of Mood Disorders.
Journal Formal name:Psychiatry and clinical neurosciences
Abbreviation:Psychiatry Clin Neurosci
ISSN code:14401819/13231316
Domestic / ForeginForegin
Volume, Issue, Page pp..
Author and coauthor Baba Hajime, Kito Shinsuke, Nukariya Kazutaka, Takeshima Minoru, Fujise Noboru, Iga Junichi, Oshibuchi Hidehiro, Kawano Masahiko, Kimura Mahiko, Mizukami Katsuyoshi, Mimura Masaru,
Publication date 2022/03/11
Summary The Committee for Treatment Guidelines of Mood Disorders, Japanese Society of Mood Disorders, published a Japanese guideline for the treatment of late-life depression in 2020. Based on that guideline, the present guideline was developed and revised to incorporate the suggestions of global experts and the latest published evidence. In the diagnosis of late-life depression, it is important to carefully differentiate it from bipolar disorders, depressive states caused by physical and organic brain disease, drug effects, and dementia, and to determine the comorbidity between late-life depression and dementia. It is necessary to fully understand the clinical characteristics and psychosocial background of late-life depression, evaluate the patient's condition, and provide basic interventions based on these factors. Problem-solving therapy, reminiscence therapy/life review therapy, and behavioral activation therapy, and other forms of psychotherapy can reduce depressive symptoms. In terms of pharmacotherapy, newer antidepressants or non-tricyclic antidepressants are recommended for late-life depression, and it is recommended that the efficacy of least the minimal effective dosage should first be determined. Switching antidepressants and aripiprazole augmentation can be used to treatment-resistant therapy. Electroconvulsive therapy and repetitive transcranial magnetic stimulation have demonstrated usefulness for late-life depression. Exercise therapy, high-intensity light therapy, and diet therapy also show some effectiveness and are useful for late-life depression. Continuation therapy should be maintained for at least 1 year after remission. This article is protected by copyright. All rights reserved.
DOI 10.1111/pcn.13349
PMID 35274788