古市 好宏
   Department   School of Medicine(Tokyo Women's Medical University Adachi Medical Center), School of Medicine
   Position   Associate Professor
Article types Case report
Language English
Peer review Peer reviewed
Title Case study to assess the safety of irreversible electroporation near the heart.
Journal Formal name:SpringerPlus
Abbreviation:Springerplus
ISSN code:21931801/21931801
Domestic / ForeginForegin
Volume, Issue, Page 4,pp.74
Author and coauthor Sugimoto Katsutoshi, Moriyasu Fuminori, Takeuchi Hirohito, Ando Mayumi, Sano Takatomo, Mori Toshifumi, Furuichi Yoshihiro, Kobayashi Yoshiyuki, Nakamura Ikuo
Publication date 2015
Summary INTRODUCTION:Irreversible electroporation (IRE) is a promising technique for the focal treatment of soft tissue tumors. Even though the local application of an excessive electric field is a potential cause of cardiac arrhythmias, initial clinical studies have shown that IRE is generally safe when cardiac gating is employed.CASE DESCRIPTION:In this case report, we observed an episode of ventricular extrasystoles without hemodynamic changes during which time the synchronization device failed to operate properly, with pulses delivered not in the absolute refractory period but in the relative refractory period.DISCUSSION AND EVALUATION:At present, persons performing IRE must keep in mind that there is a small but real risk of synchronization failure even when a cardiac synchronization device is used.CONCLUSION:It is advisable to err on the side of caution when treating lesions near the heart.
DOI 10.1186/s40064-015-0828-7
PMID 25853025