フルイチ ヨシヒロ
  古市 好宏
   所属   医学部 医学科(附属足立医療センター)
   職種   准教授
論文種別 症例報告
言語種別 英語
査読の有無 査読あり
表題 Focal nodular hyperplasia-like lesion of the liver with focal adenoma features associated with idiopathic portal hypertension.
掲載誌名 正式名:Hepatology research : the official journal of the Japan Society of Hepatology
略  称:Hepatol Res
ISSNコード:13866346/13866346
掲載区分国外
巻・号・頁 44(10),pp.E309-15
著者・共著者 Sugimoto Katsutoshi, Kondo Fukuo, Furuichi Yoshihiro, Oshiro Hisashi, Nagao Toshitaka, Saito Kazuhiro, Yoshida Hiroshi, Imai Yasuharu, Fukusato Toshio, Moriyasu Fuminori
発行年月 2014/10
概要 Great progress has been made in the diagnosis of focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) in the last few years due to the use of molecular criteria. This has allowed us to identify a new type of hepatic nodule. In this case report, we present a male patient with a hepatic nodule associated with idiopathic portal hypertension (IPH) pathologically exhibiting not only the morphological features of FNH, such as ductular reactions, dilated sinusoids, major vascular abnormalities and an immunohistochemical "map-like" pattern of glutamine synthetase (GS), but also the immunohistological features of focal HCA, such as strong expression of serum amyloid A and C-reactive protein and weak expression of GS. As the final diagnosis, the nodule was identified as an FNH-like lesion with focal inflammatory hepatocellular adenoma.
DOI 10.1111/hepr.12273
PMID 24397430