|
Yoko Kawase-Koga
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Professor and Division head |
|
| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | HIV-associated Burkitt lymphoma in a Japanese patient with early submandibular swelling. |
| Journal | Formal name：BMC research notes Abbreviation：BMC Res Notes ISSN code：17560500/17560500 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 6,pp.557 |
| Author and coauthor | Komatsu Noriko, Kawase-Koga Yoko, Mori Yoshiyuki, Kamikubo Yasuhiko, Kurokawa Mineo, Takato Tsuyoshi |
| Publication date | 2013/12 |
| Summary | BACKGROUND:Patients infected with the human immunodeficiency virus (HIV) are at risk of developing malignancies and have an increased susceptibility to infection. HIV-associated Burkitt lymphoma (BL) is relatively rare in developed countries, but remains prevalent in developing counties and is sometimes compounded by the fact that patients may be unaware that they are HIV-positive.CASE PRESENTATION:A 37-year-old Japanese man was referred to our department for diagnosis and management of submandibular swelling. He was unaware that he was HIV-positive at the initial visit. Here, we describe our diagnostic approach, in which we used hematological and immunological investigations, biopsy, fluorescence-activated cell sorting and fluorescence in situ hybridization to confirm the diagnosis of HIV-associated BL. The patient has no risk factors for HIV infection, and the source of infection remains unclear.CONCLUSIONS:In this case, submandibular swelling was the first clinical sign of pathology and the patient's HIV-positive status only became evident later. It is highly likely that BL was triggered by HIV infection. |
| DOI | 10.1186/1756-0500-6-557 |
| PMID | 24370065 |