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EGUCHI SEIICHIRO
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Assistant Professor |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | A Rare Case of Malignant Craniopharyngioma Reactive to Adjunctive Stereotactic Radiotherapy and Chemotherapy: Case Report and Literature Review. |
| Journal | Formal name：World neurosurgery Abbreviation：World Neurosurg ISSN code：18788769/18788750 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 117,pp.332-338 |
| Author and coauthor | Nomura Shunsuke†*, Aihara Yasuo, Amano Kosaku, Eguchi Seiichiro, Chiba Kentaro, Komori Takashi, Kawamata Takakazu |
| Publication date | 2018/09 |
| Summary | BACKGROUND:Malignant craniopharyngioma or anaplastic craniopharyngioma was first reported in 1987 by Akachi and colleagues. It has malignant clinical and histological features, remarkably rapid progression, atypical pathology like squamous cell carcinoma, and a poor prognosis. To date, 17 cases of malignant craniopharyngioma have been reported, most of which were secondary malignant tumors. In classic benign craniopharyngioma, adjunctive treatment after gross total removal is not necessary, but in cases of malignant tumors, adjunctive treatment is important.CASE DESCRIPTION:Here we report the first case of malignant craniopharyngioma treated with adjunctive gamma knife stereotactic radiosurgery and chemotherapy (carboplatin and etoposide, as well as temozolomide chemotherapy). Treatment effectively controlled progression of the tumor temporarily.CONCLUSIONS:Adjunctive gamma knife stereotactic radiosurgery and chemotherapy for malignant craniopharyngioma affects follow-up strategies, we propose the need for a revision to the World Health Organization classification regarding the evaluation of malignant craniopharyngioma. |
| DOI | 10.1016/j.wneu.2018.05.244 |
| PMID | 29933092 |