エグチ セイイチロウ   EGUCHI SEIICHIRO
  江口 盛一郎
   所属   医学部 医学科(東京女子医科大学病院)
   職種   助教
論文種別 症例報告
言語種別 英語
査読の有無 査読あり
表題 A Rare Case of Malignant Craniopharyngioma Reactive to Adjunctive Stereotactic Radiotherapy and Chemotherapy: Case Report and Literature Review.
掲載誌名 正式名:World neurosurgery
略  称:World Neurosurg
ISSNコード:18788769/18788750
掲載区分国外
巻・号・頁 117,pp.332-338
著者・共著者 Nomura Shunsuke†*, Aihara Yasuo, Amano Kosaku, Eguchi Seiichiro, Chiba Kentaro, Komori Takashi, Kawamata Takakazu
発行年月 2018/09
概要 BACKGROUND:Malignant craniopharyngioma or anaplastic craniopharyngioma was first reported in 1987 by Akachi and colleagues. It has malignant clinical and histological features, remarkably rapid progression, atypical pathology like squamous cell carcinoma, and a poor prognosis. To date, 17 cases of malignant craniopharyngioma have been reported, most of which were secondary malignant tumors. In classic benign craniopharyngioma, adjunctive treatment after gross total removal is not necessary, but in cases of malignant tumors, adjunctive treatment is important.CASE DESCRIPTION:Here we report the first case of malignant craniopharyngioma treated with adjunctive gamma knife stereotactic radiosurgery and chemotherapy (carboplatin and etoposide, as well as temozolomide chemotherapy). Treatment effectively controlled progression of the tumor temporarily.CONCLUSIONS:Adjunctive gamma knife stereotactic radiosurgery and chemotherapy for malignant craniopharyngioma affects follow-up strategies, we propose the need for a revision to the World Health Organization classification regarding the evaluation of malignant craniopharyngioma.
DOI 10.1016/j.wneu.2018.05.244
PMID 29933092